Resident Evil Requiem: Lockpick and Locked Container Guide
Games

Resident Evil Requiem: Lockpick and Locked Container Guide

authorBy Amy Hennig
DateFeb 27, 2026
Read time3 min

In the survival horror game, Resident Evil Requiem, players will encounter various challenges and hidden items as they navigate the desolate Care Center. Among these crucial finds are lockpicks, instrumental for unlocking secret compartments scattered throughout the facility. This guide aims to provide a thorough walkthrough, detailing the exact locations of all lockpicks and the corresponding locked drawers and lockers, ensuring players can uncover valuable resources and advance their gameplay experience.

As you delve deeper into the mysterious Care Center, playing as Grace, the acquisition of lockpicks becomes paramount. These tools are not merely collectibles but gateways to essential crafting materials, particularly rare metals needed to forge potent Requiem ammunition. The strategic collection and utilization of these items are critical for survival and progression, demanding players to meticulously explore and sometimes backtrack to maximize their inventory and combat capabilities.

Discovering Every Lockpick in Resident Evil Requiem

In Resident Evil Requiem, specifically within the eerie confines of the Care Center, five lockpicks are strategically placed to aid Grace in her quest. These invaluable tools are distributed across three primary sections of the facility: one in the East Wing, two in the West Wing, and two more tucked away in the Basement. Each lockpick is a single-use item, consumed upon opening a locked drawer or locker. Therefore, efficient planning and exploration are crucial for players aiming to uncover all hidden secrets and resources the game has to offer.

The journey to collect these lockpicks begins in the Lead Researcher's Office in the East Wing, where the first one awaits on a small cabinet. Moving into the West Wing, players will find the second lockpick within a locker in the Custodian's Office, accessible with a Level 1 wristband. The third is located on a desk in an Office on the second floor of the West Wing, requiring players to ascend stairs near the Custodian's Office. Descending to the Basement, the fourth lockpick is found in the Boiler Room, necessitating careful navigation through a broken fence to avoid an electrified water hazard. Finally, the fifth lockpick is situated in a tunnel connecting the Workshop to the Inspection area, reachable by utilizing a Square Socket Wrench to open a vent or by inserting a joint plug into an outlet near the Furnace.

Unlocking All Hidden Compartments

Within Resident Evil Requiem, the Care Center harbors five specific locked containers—three drawers and two lockers—all requiring a lockpick to access. Each of these compartments yields a rare metal, a vital component for crafting Requiem ammo once Grace learns the recipe from the Blood Specimen (Converged). Players need not worry if they miss early opportunities, as the game's progression allows for revisiting upper floors to unlock these containers before the campaign concludes, emphasizing the importance of thorough exploration to secure these valuable resources.

The search for these locked containers begins in the East Wing Lobby, where a locked drawer is found within a cabinet on the south side. The second locked drawer is located in the West Wing's first-floor corridor, south of the Restroom and near the Kitchen, beside some sofas. A third locked drawer awaits outside the Chairman's Office on the second floor of the West Wing, adjacent to the door. In the Basement, the Bunkroom, accessible with a joint plug, contains a leftmost blue locker that can be lockpicked. Finally, after acquiring the Forklift Key, players can enter the Inspection room, where the left of two blue lockers on the northeast side holds the last hidden item, ensuring players have ample opportunity to gather all necessary crafting materials for their survival.

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